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Results for "

phospholipid compound

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Liposome (3) Phospholipase (5)
By Research Areas:	Cancer (2) Inflammation/Immunology (3) Metabolic Disease (4) Neurological Disease (5)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W441007

DSPE-Mal	Liposome	Inflammation/Immunology Cancer
DSPE-MAL is a thiol reactive a **phospholipid compound*. DSPE-MAL has two saturated fatty acids and can self-assemble in water to form lipid* bilayer. DSPE-MAL can be used to prepare liposomes as agent nanocarrier .

HY-W322575

1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine DHPC	Others	Others
1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine (DHPC) is a biologically active phospholipid compound and a derivative of phosphatidylcholine (PC) .

HY-W441011

DSPE-NHS	Liposome	Neurological Disease Inflammation/Immunology Cancer
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-W441017

DSPE-SPDP	Liposome	Others
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .

HY-118431

DMABA NHS ester	Others	Others
DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .

HY-145384

ROC-0929	Phospholipase	Inflammation/Immunology
ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A₂ (sPLA₂s) with an IC₅₀ of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s) are a family of disulfide-rich, Ca ²⁺-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .

HY-142669

Lp-PLA2-IN-4	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38) .

HY-142670

Lp-PLA2-IN-5	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-5 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-5 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 32) .

HY-142779

Lp-PLA2-IN-11	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145) .

HY-142778

Lp-PLA2-IN-10	Phospholipase	Neurological Disease Metabolic Disease
Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-10 has the potential for the research of neurodegenerative-related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis (extracted from patent WO2022001881A1, compound 4) .

Cat. No.	Product Name

HY-L043

Lipid Compound Library	1352 compounds
Lipids are a diverse and ubiquitous group of compounds which have many key biological functions, such as acting as structural components of cell membranes, serving as energy storage sources and participating in signaling pathways. Several studies suggest that bioactive lipids have effects on the treatment of some mental illnesses and metabolic syndrome. For example, DHA and EPA are important for monoaminergic neurotransmission, brain development and synaptic functioning, and are also correlated with a reduced risk of cancer and cardiovascular disease in clinical and animal studies. MCE supplies a unique collection of 1352 lipid and lipid derivative related compounds including triglycerides, phospholipids, sphingolipids, steroids and their structural analogues or derivatives. MCE lipid compound library can be used for research in bioactive lipids, and high throughput screening (HTS) and high content screening (HCS).

Lipid Compound Library

1352 compounds

Lipids are a diverse and ubiquitous group of compounds which have many key biological functions, such as acting as structural components of cell membranes, serving as energy storage sources and participating in signaling pathways. Several studies suggest that bioactive lipids have effects on the treatment of some mental illnesses and metabolic syndrome. For example, DHA and EPA are important for monoaminergic neurotransmission, brain development and synaptic functioning, and are also correlated with a reduced risk of cancer and cardiovascular disease in clinical and animal studies.

MCE supplies a unique collection of 1352 lipid and lipid derivative related compounds including triglycerides, phospholipids, sphingolipids, steroids and their structural analogues or derivatives. MCE lipid compound library can be used for research in bioactive lipids, and high throughput screening (HTS) and high content screening (HCS).

HY-L091

Lipid Metabolism Compound Library	650 compounds
Lipids are a fundamental class of organic molecules implicated in a wide range of biological processes, and based on this can be broadly classified into five categories: fatty acids, triacylglycerols (TAGs), phospholipids, sterol lipids and sphingolipids. Lipids play a crucial role in different metabolic pathways and cellular functions. Lipid metabolism is an important physiological process that is related to nutrient adjustment, hormone regulation, and homeostasis. Lipid metabolism dysregulation is associated with many diseases such as obesity, liver disease, aging and inflammation. MCE offers a unique collection of 650 compounds related to lipid metabolism, which target relevant targets in the process of lipid metabolism, such as ATGL, MAGL, FAAH, acetyl-Coa Carboxylase, FASN, etc. MCE lipid metabolism compound library is a useful tool for research lipid metabolism and drug discovery of diseases related to lipid metabolism.

Lipid Metabolism Compound Library

650 compounds

Lipids are a fundamental class of organic molecules implicated in a wide range of biological processes, and based on this can be broadly classified into five categories: fatty acids, triacylglycerols (TAGs), phospholipids, sterol lipids and sphingolipids. Lipids play a crucial role in different metabolic pathways and cellular functions. Lipid metabolism is an important physiological process that is related to nutrient adjustment, hormone regulation, and homeostasis. Lipid metabolism dysregulation is associated with many diseases such as obesity, liver disease, aging and inflammation.

MCE offers a unique collection of 650 compounds related to lipid metabolism, which target relevant targets in the process of lipid metabolism, such as ATGL, MAGL, FAAH, acetyl-Coa Carboxylase, FASN, etc. MCE lipid metabolism compound library is a useful tool for research lipid metabolism and drug discovery of diseases related to lipid metabolism.

DSPE-Mal	Drug Delivery
DSPE-MAL is a thiol reactive a **phospholipid compound*. DSPE-MAL has two saturated fatty acids and can self-assemble in water to form lipid* bilayer. DSPE-MAL can be used to prepare liposomes as agent nanocarrier .

DSPE-NHS	Drug Delivery
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

DSPE-SPDP	Drug Delivery
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .

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